Antioxidant and Antibacterial Activity of Organic Extracts of Roots of <i>Glycyrrhiza Glabra Linn</i>

Zafar Iqbal; Zhang Hai; Hong Yan Ping; Abdul Ghaffar; Munaza Mumtaz; Luban Liaqat

doi:doi:10.11648/j.plant.20170504.12

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Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn

Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, Luban Liaqat

Published in Plant (Volume 5, Issue 4)

Received: 7 March 2017 Accepted: 27 March 2017 Published: 30 October 2017

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Abstract

Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.

Published in	Plant (Volume 5, Issue 4)
DOI	10.11648/j.plant.20170504.12
Page(s)	68-72
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Glycyrrhiza Glabra Linn, Orgnic Extracts, Antioxidant, Antibacterials

References

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APA Style

Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. (2017). Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant, 5(4), 68-72. https://doi.org/10.11648/j.plant.20170504.12

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ACS Style

Zafar Iqbal; Zhang Hai; Hong Yan Ping; Abdul Ghaffar; Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017, 5(4), 68-72. doi: 10.11648/j.plant.20170504.12

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AMA Style

Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017;5(4):68-72. doi: 10.11648/j.plant.20170504.12

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@article{10.11648/j.plant.20170504.12,
  author = {Zafar Iqbal and Zhang Hai and Hong Yan Ping and Abdul Ghaffar and Munaza Mumtaz and Luban Liaqat},
  title = {Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn},
  journal = {Plant},
  volume = {5},
  number = {4},
  pages = {68-72},
  doi = {10.11648/j.plant.20170504.12},
  url = {https://doi.org/10.11648/j.plant.20170504.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20170504.12},
  abstract = {Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.},
 year = {2017}
}

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TY  - JOUR
T1  - Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn
AU  - Zafar Iqbal
AU  - Zhang Hai
AU  - Hong Yan Ping
AU  - Abdul Ghaffar
AU  - Munaza Mumtaz
AU  - Luban Liaqat
Y1  - 2017/10/30
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.20170504.12
DO  - 10.11648/j.plant.20170504.12
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 68
EP  - 72
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.20170504.12
AB  - Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.
VL  - 5
IS  - 4
ER  -

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Author Information

Zafar Iqbal

Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan
Zhang Hai

School of Chemistry and Chemical Engineering, Qianbei Featured Resources, Applied Research Key Laboratory, Zunyi Normal College, Guizhou, Zunyi, China
Hong Yan Ping

Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engineering, Jiangxi, Agriculutural University, Nanchang, China
Abdul Ghaffar

Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan
Munaza Mumtaz

Department of Applied Chemistry, University of Engineering and Technology, Lahore, Pakistan
Luban Liaqat

Applied Chemistry Research Centre, PCSIR Laboratories Complex, Lahore, Pakistan

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APA Style

Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. (2017). Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant, 5(4), 68-72. https://doi.org/10.11648/j.plant.20170504.12

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ACS Style

Zafar Iqbal; Zhang Hai; Hong Yan Ping; Abdul Ghaffar; Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017, 5(4), 68-72. doi: 10.11648/j.plant.20170504.12

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AMA Style

Zafar Iqbal, Zhang Hai, Hong Yan Ping, Abdul Ghaffar, Munaza Mumtaz, et al. Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn. Plant. 2017;5(4):68-72. doi: 10.11648/j.plant.20170504.12

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@article{10.11648/j.plant.20170504.12,
  author = {Zafar Iqbal and Zhang Hai and Hong Yan Ping and Abdul Ghaffar and Munaza Mumtaz and Luban Liaqat},
  title = {Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn},
  journal = {Plant},
  volume = {5},
  number = {4},
  pages = {68-72},
  doi = {10.11648/j.plant.20170504.12},
  url = {https://doi.org/10.11648/j.plant.20170504.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.20170504.12},
  abstract = {Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.},
 year = {2017}
}

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TY  - JOUR
T1  - Antioxidant and Antibacterial Activity of Organic Extracts of Roots of Glycyrrhiza Glabra Linn
AU  - Zafar Iqbal
AU  - Zhang Hai
AU  - Hong Yan Ping
AU  - Abdul Ghaffar
AU  - Munaza Mumtaz
AU  - Luban Liaqat
Y1  - 2017/10/30
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.20170504.12
DO  - 10.11648/j.plant.20170504.12
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 68
EP  - 72
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.20170504.12
AB  - Extacts of root of Glycyrrhiza glabra linn were prepared by using n-hexan, toluene, tetrahydrofuran, ethylacetate, and ethanol and their antioxidant and antimicrobial activities were measured. Secondary metalbilites like flavonoids, alkaloids, terpenoids, glycosides, and steroids were measured and it was found that highly polar solvents ike ethyl alcohol, ethyl acetate and THF extract more metabolites as compared to less polar solvents. In vitro antioxidant activity of organic extracts of glycyrrhiza glabra root was measured by using DPPH scavenging radicle. Ethanolic extract gave highest antioxidant activity of 92% followed by ethyl acetate 89%, THF 87%, toluene 45% and hexane 23% respectively. The organic extracts of the plant root was further tested for its antibacterial activity against two bacteria viz. Staphylococcus aureus and Escherichia coli. Ethanolic extract and THF extracts have showed mild antibacterial activity against saphylococcus aureus and escherichia coli respectively whereas n-hexane extract failed to inhibit the growth of bacteria. The results have shown that organic extract of Glycyrrhiza glabra linn is rich source of secondary metabolites, a strong antioxidant and possess mild antibacterial activity.
VL  - 5
IS  - 4
ER  -

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