Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes

Kenneth Anchang Yongabi; Florence Titu Manjong; Mary Chia Garba; Daniel Martinez-Carrera

doi:doi:10.11648/j.ajcem.s.2015030101.17

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Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes

Kenneth Anchang Yongabi, Florence Titu Manjong, Mary Chia Garba, Daniel Martinez-Carrera

Published in American Journal of Clinical and Experimental Medicine (Volume 3, Issue 1-1)

Received: 25 December 2014 Accepted: 30 December 2014 Published: 27 February 2015

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Abstract

This is a preliminary case reports of the healing potential of Cameroonian traditional foods used since time immemorial and now used to enhance the immune systems of patients of HIV patients with lessons that can be applied in the clinical management of Ebola hemorrhagic fevers. Dietary supplements was made from 0.9% salt and aqueous extracts of Flammiluna spp, Termytomyes titanicus and Pleurotus ostreatus.These macrofungi have been used in African traditional medicine and traditional diets for the management of HIV /AIDS and its accompanying opportunistic infections amongst tribes in north west Cameroon. The study indicated that the prevalence of HIV/AIDS in North West region of Cameroon is increasing with girls and women having the highest rate of infection (60%) with increasing shortage of antiretroviral drugs especially in the rural areas of that region.Approximately,95% of patients encountered in this study even when receiving antiretroviral drugs still depend on Traditional medicines. More than 98% of patients in the rural areas who are seropositive but with a CD4 counts of more than 400 cells/ml sustain their lives on African nutritional supplements and traditional medicines.Phytobiotechnology Research laboratories documented 23 mushroom species belonging to 23 families used in various therapeutic preparation for the management of HIV/AIDS in rural North west region of Cameroon. From this Flammiluna, Termitomyces and pleurotus were selected as they are frequently used and available.They were extracted and used in combination in the management of HIV/AIDS patients at the Phytobiotechnology Research Clinic. From 1000 patients who consented through an ethical clearance process to follow the intervention,600 were already receiving antiretroviral drugs from the regional hospital,while on this supplements an increase of CD4 counts(Facs count method,Beckton Dickenson) by 85% was observed with a 94% decrease in Viral loads(Viral load machine,ABI Prism 7300,Biocentric method applied).For the 400 patients who were not qualify to receive ART, a 95% increase in CD4 counts and 95% decrease in Viral loads were recorded. In all study groups,an 80% increase in body weight, clearance of frequent fevers, dysentery and diarrhea symptoms ceased.Haematological analyses indicated 70% in White blood cell counts with a balance neutrophils and lymphocyte counts. Conclusions from this studies stresses the potentials of medicinal food supplementation in the effective management of HIV/AIDS with potential application to other viral diseases such as Ebola hemorrhagic fevers in Africa.

Published in	American Journal of Clinical and Experimental Medicine (Volume 3, Issue 1-1) This article belongs to the Special Issue Clinical Innovations, Developments in the Diagnosis, Management and Prevention of Ebola Disease (Marburg fever) and Hemorrhagic Fevers
DOI	10.11648/j.ajcem.s.2015030101.17
Page(s)	33-37
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Diet, Nutrition, Supplementation, Traditional Food Plants, HIV/AIDS, Ebola Virus, Lessons

References

[1]	Ramadhani, H. O. N. M. Thielman, K. Z. Landman et al., “Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania,” Clinical Infectious Diseases, vol. 45, no. 11, pp. 1492–1498, 2007.
[2]	Kenneth.A.Yongabi and Mary Chia-Garba , Incidence of Babesia infection causing pyrexia of unknown origin (PUO) amongst HIV/AIDS patients in Cameroon, American Journal of Research Communications, Vol. 2 (10) ISSN:2325-4076, (2014)
[3]	Yongabi,K.A; Fon,E.F; Lukong,H; Chia, P.N A Preliminary Assessment of Cucurbita maxima leaves from Cameroon on heamatological parameters in albino rats. Journal of Molecular pharmaceutics and Organic Process Research,2:117.DOI:10.4172/2329-9053.1000117, (2014)
[4]	Kenneth Yongabi Anchang (2014) Current Developments in Mushroom Biotechnology in Sub Saharan Africa. World Society for Mushroom Biology Mushroom Production (WSMBMP) Bulletin 11: July 31
[5]	Yongabi,K.A;Adotey,G;Chia,P.N and Temate Tiagueu,Y (2014) Preliminary Report on Management of of HIV/AIDS-associated opportunistic Skin Infections with PhytodermTM a natural myco-based cream. Pp.19 Journal of Molecular pharmaceutics and Organic Process Research
[6]	Kanters, M. Nansubuga, D. Mwehire, et al., “Increased mortality among HIV-positive men on antiretroviral therapy: survival differences between sexes explained by late initiation in Uganda,” Journal of HIV/AIDS (Auckland), vol. 5, pp. 111–119, 2013.
[7]	Sieleunou, M. Souleymanou, A.-M. Schönenberger, J. Menten, and M. Boelaert, “Determinants of survival in AIDS patients on antiretroviral therapy in a rural centre in the Far-North Province, Cameroon,” Tropical Medicine and International Health, vol. 14, no. 1, pp. 36–43, 2009.
[8]	R. R. Allam, M. V. Murhekar, T. Bhatnagar, et al., “Survival probability and predictors of mortality and retention in care among patients enrolled for first-line antiretroviral therapy,” Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 108, no. 4, pp. 198–205, 2008
[9]	Yantao Jin,1,2 Xin Wang,3 Zhengwei Li,1 Ziqiang Jiang,1 Huijun Guo,1,4 Zhibin Liu,1 and Liran Xu1,4 (2014) Survival of AIDS Patients Treated with Traditional Chinese Medicine in Rural Central China: A Retrospective Cohort Study, 2004–2012, Evidence-Based Complementary and Alternative MedicineArticle ID 282819
[10]	Y. Jin, Z. Liu, X. Wang, et al., “A systematic review of cohort studies of the quality of life in HIV/AIDS patients after antiretroviral therapy,” International Journal of STD & AIDS, vol. 25, no. 11, pp. 771–777, 2014.

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Kenneth Anchang Yongabi, Florence Titu Manjong, Mary Chia Garba, Daniel Martinez-Carrera. (2015). Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. American Journal of Clinical and Experimental Medicine, 3(1-1), 33-37. https://doi.org/10.11648/j.ajcem.s.2015030101.17

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Kenneth Anchang Yongabi; Florence Titu Manjong; Mary Chia Garba; Daniel Martinez-Carrera. Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. Am. J. Clin. Exp. Med. 2015, 3(1-1), 33-37. doi: 10.11648/j.ajcem.s.2015030101.17

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Kenneth Anchang Yongabi, Florence Titu Manjong, Mary Chia Garba, Daniel Martinez-Carrera. Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. Am J Clin Exp Med. 2015;3(1-1):33-37. doi: 10.11648/j.ajcem.s.2015030101.17

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@article{10.11648/j.ajcem.s.2015030101.17,
  author = {Kenneth Anchang Yongabi and Florence Titu Manjong and Mary Chia Garba and Daniel Martinez-Carrera},
  title = {Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {1-1},
  pages = {33-37},
  doi = {10.11648/j.ajcem.s.2015030101.17},
  url = {https://doi.org/10.11648/j.ajcem.s.2015030101.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.s.2015030101.17},
  abstract = {This is a preliminary case reports of the healing potential of Cameroonian traditional foods used since time immemorial and now used to enhance the immune systems of patients of HIV patients with lessons that can be applied in the clinical management of Ebola hemorrhagic fevers. Dietary supplements  was made from 0.9% salt and aqueous extracts of Flammiluna spp, Termytomyes titanicus and Pleurotus ostreatus.These macrofungi have been used in African traditional medicine and traditional diets  for the management of HIV /AIDS and its accompanying opportunistic infections amongst tribes in north west Cameroon. The study indicated that the prevalence of HIV/AIDS in North West region of Cameroon is increasing with girls and women having the highest rate of infection (60%) with increasing shortage of antiretroviral drugs especially in the rural areas of that region.Approximately,95% of patients encountered in this study even when receiving antiretroviral drugs still depend on Traditional medicines. More than 98% of patients in the rural areas who are seropositive but with a CD4 counts of more than 400 cells/ml sustain their lives on African nutritional supplements and traditional medicines.Phytobiotechnology Research laboratories documented 23 mushroom species belonging to 23 families used in various therapeutic preparation for the management of HIV/AIDS in rural North west region of Cameroon. From this Flammiluna, Termitomyces and pleurotus were selected as they are frequently used and available.They were extracted and used in combination in the management of HIV/AIDS patients at the Phytobiotechnology Research Clinic. From 1000 patients who consented  through an ethical clearance process to follow the intervention,600 were already receiving antiretroviral drugs from the regional hospital,while on this supplements an increase of CD4 counts(Facs count method,Beckton Dickenson) by 85% was observed with a 94% decrease in Viral loads(Viral load machine,ABI Prism 7300,Biocentric method applied).For the 400 patients who were not qualify to receive ART, a 95% increase in CD4 counts and 95% decrease in Viral loads were recorded. In all study groups,an 80% increase in body weight, clearance of frequent fevers, dysentery and diarrhea symptoms ceased.Haematological analyses indicated 70% in White blood cell counts with a balance neutrophils and lymphocyte counts. Conclusions from this studies stresses the potentials of medicinal food supplementation in the effective management of HIV/AIDS with potential application to other viral diseases such as Ebola hemorrhagic fevers in Africa.},
 year = {2015}
}

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TY  - JOUR
T1  - Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes
AU  - Kenneth Anchang Yongabi
AU  - Florence Titu Manjong
AU  - Mary Chia Garba
AU  - Daniel Martinez-Carrera
Y1  - 2015/02/27
PY  - 2015
N1  - https://doi.org/10.11648/j.ajcem.s.2015030101.17
DO  - 10.11648/j.ajcem.s.2015030101.17
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 33
EP  - 37
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.s.2015030101.17
AB  - This is a preliminary case reports of the healing potential of Cameroonian traditional foods used since time immemorial and now used to enhance the immune systems of patients of HIV patients with lessons that can be applied in the clinical management of Ebola hemorrhagic fevers. Dietary supplements  was made from 0.9% salt and aqueous extracts of Flammiluna spp, Termytomyes titanicus and Pleurotus ostreatus.These macrofungi have been used in African traditional medicine and traditional diets  for the management of HIV /AIDS and its accompanying opportunistic infections amongst tribes in north west Cameroon. The study indicated that the prevalence of HIV/AIDS in North West region of Cameroon is increasing with girls and women having the highest rate of infection (60%) with increasing shortage of antiretroviral drugs especially in the rural areas of that region.Approximately,95% of patients encountered in this study even when receiving antiretroviral drugs still depend on Traditional medicines. More than 98% of patients in the rural areas who are seropositive but with a CD4 counts of more than 400 cells/ml sustain their lives on African nutritional supplements and traditional medicines.Phytobiotechnology Research laboratories documented 23 mushroom species belonging to 23 families used in various therapeutic preparation for the management of HIV/AIDS in rural North west region of Cameroon. From this Flammiluna, Termitomyces and pleurotus were selected as they are frequently used and available.They were extracted and used in combination in the management of HIV/AIDS patients at the Phytobiotechnology Research Clinic. From 1000 patients who consented  through an ethical clearance process to follow the intervention,600 were already receiving antiretroviral drugs from the regional hospital,while on this supplements an increase of CD4 counts(Facs count method,Beckton Dickenson) by 85% was observed with a 94% decrease in Viral loads(Viral load machine,ABI Prism 7300,Biocentric method applied).For the 400 patients who were not qualify to receive ART, a 95% increase in CD4 counts and 95% decrease in Viral loads were recorded. In all study groups,an 80% increase in body weight, clearance of frequent fevers, dysentery and diarrhea symptoms ceased.Haematological analyses indicated 70% in White blood cell counts with a balance neutrophils and lymphocyte counts. Conclusions from this studies stresses the potentials of medicinal food supplementation in the effective management of HIV/AIDS with potential application to other viral diseases such as Ebola hemorrhagic fevers in Africa.
VL  - 3
IS  - 1-1
ER  -

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Author Information

Kenneth Anchang Yongabi

Tropical Infectious Diseases and public Health Engineering Research Group (TIDPHERG), Phytobiotechnology Research Foundation Institute, Catholic University of Cameroon, Bamenda, Bamenda, Cameroon
Florence Titu Manjong

Department of Health Economics, Policy and Management, Catholic University of Cameroon, Bamenda
Mary Chia Garba

Faculty of Medical Sciences, University of Bamenda, Cameroon
Daniel Martinez-Carrera

Biotecnologia de Hongos Comestibles, Colegio de Posgraduados, Campus Puebla, Puebla, Mexico

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APA Style

Kenneth Anchang Yongabi, Florence Titu Manjong, Mary Chia Garba, Daniel Martinez-Carrera. (2015). Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. American Journal of Clinical and Experimental Medicine, 3(1-1), 33-37. https://doi.org/10.11648/j.ajcem.s.2015030101.17

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ACS Style

Kenneth Anchang Yongabi; Florence Titu Manjong; Mary Chia Garba; Daniel Martinez-Carrera. Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. Am. J. Clin. Exp. Med. 2015, 3(1-1), 33-37. doi: 10.11648/j.ajcem.s.2015030101.17

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AMA Style

Kenneth Anchang Yongabi, Florence Titu Manjong, Mary Chia Garba, Daniel Martinez-Carrera. Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes. Am J Clin Exp Med. 2015;3(1-1):33-37. doi: 10.11648/j.ajcem.s.2015030101.17

Copy | Download

@article{10.11648/j.ajcem.s.2015030101.17,
  author = {Kenneth Anchang Yongabi and Florence Titu Manjong and Mary Chia Garba and Daniel Martinez-Carrera},
  title = {Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {3},
  number = {1-1},
  pages = {33-37},
  doi = {10.11648/j.ajcem.s.2015030101.17},
  url = {https://doi.org/10.11648/j.ajcem.s.2015030101.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.s.2015030101.17},
  abstract = {This is a preliminary case reports of the healing potential of Cameroonian traditional foods used since time immemorial and now used to enhance the immune systems of patients of HIV patients with lessons that can be applied in the clinical management of Ebola hemorrhagic fevers. Dietary supplements  was made from 0.9% salt and aqueous extracts of Flammiluna spp, Termytomyes titanicus and Pleurotus ostreatus.These macrofungi have been used in African traditional medicine and traditional diets  for the management of HIV /AIDS and its accompanying opportunistic infections amongst tribes in north west Cameroon. The study indicated that the prevalence of HIV/AIDS in North West region of Cameroon is increasing with girls and women having the highest rate of infection (60%) with increasing shortage of antiretroviral drugs especially in the rural areas of that region.Approximately,95% of patients encountered in this study even when receiving antiretroviral drugs still depend on Traditional medicines. More than 98% of patients in the rural areas who are seropositive but with a CD4 counts of more than 400 cells/ml sustain their lives on African nutritional supplements and traditional medicines.Phytobiotechnology Research laboratories documented 23 mushroom species belonging to 23 families used in various therapeutic preparation for the management of HIV/AIDS in rural North west region of Cameroon. From this Flammiluna, Termitomyces and pleurotus were selected as they are frequently used and available.They were extracted and used in combination in the management of HIV/AIDS patients at the Phytobiotechnology Research Clinic. From 1000 patients who consented  through an ethical clearance process to follow the intervention,600 were already receiving antiretroviral drugs from the regional hospital,while on this supplements an increase of CD4 counts(Facs count method,Beckton Dickenson) by 85% was observed with a 94% decrease in Viral loads(Viral load machine,ABI Prism 7300,Biocentric method applied).For the 400 patients who were not qualify to receive ART, a 95% increase in CD4 counts and 95% decrease in Viral loads were recorded. In all study groups,an 80% increase in body weight, clearance of frequent fevers, dysentery and diarrhea symptoms ceased.Haematological analyses indicated 70% in White blood cell counts with a balance neutrophils and lymphocyte counts. Conclusions from this studies stresses the potentials of medicinal food supplementation in the effective management of HIV/AIDS with potential application to other viral diseases such as Ebola hemorrhagic fevers in Africa.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Preliminary Case Reports of Dietary Supplementation from Cameroonian Traditional Food Plants for the Therapeutic Management of HIV/AIDs Patients: Adapting Such Lessons for Clinical Management of Hemorrhagic Syndromes
AU  - Kenneth Anchang Yongabi
AU  - Florence Titu Manjong
AU  - Mary Chia Garba
AU  - Daniel Martinez-Carrera
Y1  - 2015/02/27
PY  - 2015
N1  - https://doi.org/10.11648/j.ajcem.s.2015030101.17
DO  - 10.11648/j.ajcem.s.2015030101.17
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 33
EP  - 37
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.s.2015030101.17
AB  - This is a preliminary case reports of the healing potential of Cameroonian traditional foods used since time immemorial and now used to enhance the immune systems of patients of HIV patients with lessons that can be applied in the clinical management of Ebola hemorrhagic fevers. Dietary supplements  was made from 0.9% salt and aqueous extracts of Flammiluna spp, Termytomyes titanicus and Pleurotus ostreatus.These macrofungi have been used in African traditional medicine and traditional diets  for the management of HIV /AIDS and its accompanying opportunistic infections amongst tribes in north west Cameroon. The study indicated that the prevalence of HIV/AIDS in North West region of Cameroon is increasing with girls and women having the highest rate of infection (60%) with increasing shortage of antiretroviral drugs especially in the rural areas of that region.Approximately,95% of patients encountered in this study even when receiving antiretroviral drugs still depend on Traditional medicines. More than 98% of patients in the rural areas who are seropositive but with a CD4 counts of more than 400 cells/ml sustain their lives on African nutritional supplements and traditional medicines.Phytobiotechnology Research laboratories documented 23 mushroom species belonging to 23 families used in various therapeutic preparation for the management of HIV/AIDS in rural North west region of Cameroon. From this Flammiluna, Termitomyces and pleurotus were selected as they are frequently used and available.They were extracted and used in combination in the management of HIV/AIDS patients at the Phytobiotechnology Research Clinic. From 1000 patients who consented  through an ethical clearance process to follow the intervention,600 were already receiving antiretroviral drugs from the regional hospital,while on this supplements an increase of CD4 counts(Facs count method,Beckton Dickenson) by 85% was observed with a 94% decrease in Viral loads(Viral load machine,ABI Prism 7300,Biocentric method applied).For the 400 patients who were not qualify to receive ART, a 95% increase in CD4 counts and 95% decrease in Viral loads were recorded. In all study groups,an 80% increase in body weight, clearance of frequent fevers, dysentery and diarrhea symptoms ceased.Haematological analyses indicated 70% in White blood cell counts with a balance neutrophils and lymphocyte counts. Conclusions from this studies stresses the potentials of medicinal food supplementation in the effective management of HIV/AIDS with potential application to other viral diseases such as Ebola hemorrhagic fevers in Africa.
VL  - 3
IS  - 1-1
ER  -

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