Oral pathogenic gram-positive bacteria, Streptococcus pyogenes (Strept.pyogenes) are caused severe human diseases with complications, including rheumatic fever, sepsis, severe soft-tissue invasion, and toxic-shock-like syndrome (TSLS). Whereas, Streptococcus mutants(Strept. mutans),described a key causative agent of caries and infective endocarditis. Therefore, the aim of this study was to evaluate the inhibitory effect of Curcumin on Strept. mutans and Strept.pyogenes growth in comparison with the antibiotic Ciprofloxacin using well diffusion method. Minimum Inhibitory Concentration (MICs) showed that curcumin-mediated growth inhibition of Strept. mutans and, Strept. pyogenes. Results showed that curcumin significantly inhibitedthe activity of Strept. mutans and Strept. pyogenes growth with inhibition zones, 9.7mm and 10.2 mm, respectively while the inhibition zone of Ciprofloxacin 15.52mm to 13.4mm against Strept. mutans, Strept. pyogenes respectively.The antimicrobial activity of curcumin on Strept. mutans and Strept. pyogenes growth suggests that the curcumin may be useful for controlling dental biofilms, subsequently dental caries formation.This study provides significant insights into the therapeutic effect of curcumin against pathogenic gram positive bacteria, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of curcumin.
| Published in |
Automation, Control and Intelligent Systems (Volume 3, Issue 2-1)
This article belongs to the Special Issue Artificial Nano Sensory System |
| DOI | 10.11648/j.acis.s.2015030201.14 |
| Page(s) | 18-21 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Curcumin, Antibacterial Activity, Minimum Inhibitory Concentration (MIC)
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APA Style
Najah A. Mohammed, Neama Y. Habil. (2015). Evaluation of Antimicrobial Activity of Curcumin Against Two Oral Bacteria. Automation, Control and Intelligent Systems, 3(2-1), 18-21. https://doi.org/10.11648/j.acis.s.2015030201.14
ACS Style
Najah A. Mohammed; Neama Y. Habil. Evaluation of Antimicrobial Activity of Curcumin Against Two Oral Bacteria. Autom. Control Intell. Syst. 2015, 3(2-1), 18-21. doi: 10.11648/j.acis.s.2015030201.14
AMA Style
Najah A. Mohammed, Neama Y. Habil. Evaluation of Antimicrobial Activity of Curcumin Against Two Oral Bacteria. Autom Control Intell Syst. 2015;3(2-1):18-21. doi: 10.11648/j.acis.s.2015030201.14
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Download@article{10.11648/j.acis.s.2015030201.14,
author = {Najah A. Mohammed and Neama Y. Habil},
title = {Evaluation of Antimicrobial Activity of Curcumin Against Two Oral Bacteria},
journal = {Automation, Control and Intelligent Systems},
volume = {3},
number = {2-1},
pages = {18-21},
doi = {10.11648/j.acis.s.2015030201.14},
url = {https://doi.org/10.11648/j.acis.s.2015030201.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.acis.s.2015030201.14},
abstract = {Oral pathogenic gram-positive bacteria, Streptococcus pyogenes (Strept.pyogenes) are caused severe human diseases with complications, including rheumatic fever, sepsis, severe soft-tissue invasion, and toxic-shock-like syndrome (TSLS). Whereas, Streptococcus mutants(Strept. mutans),described a key causative agent of caries and infective endocarditis. Therefore, the aim of this study was to evaluate the inhibitory effect of Curcumin on Strept. mutans and Strept.pyogenes growth in comparison with the antibiotic Ciprofloxacin using well diffusion method. Minimum Inhibitory Concentration (MICs) showed that curcumin-mediated growth inhibition of Strept. mutans and, Strept. pyogenes. Results showed that curcumin significantly inhibitedthe activity of Strept. mutans and Strept. pyogenes growth with inhibition zones, 9.7mm and 10.2 mm, respectively while the inhibition zone of Ciprofloxacin 15.52mm to 13.4mm against Strept. mutans, Strept. pyogenes respectively.The antimicrobial activity of curcumin on Strept. mutans and Strept. pyogenes growth suggests that the curcumin may be useful for controlling dental biofilms, subsequently dental caries formation.This study provides significant insights into the therapeutic effect of curcumin against pathogenic gram positive bacteria, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of curcumin.},
year = {2015}
}
TY - JOUR T1 - Evaluation of Antimicrobial Activity of Curcumin Against Two Oral Bacteria AU - Najah A. Mohammed AU - Neama Y. Habil Y1 - 2015/01/27 PY - 2015 N1 - https://doi.org/10.11648/j.acis.s.2015030201.14 DO - 10.11648/j.acis.s.2015030201.14 T2 - Automation, Control and Intelligent Systems JF - Automation, Control and Intelligent Systems JO - Automation, Control and Intelligent Systems SP - 18 EP - 21 PB - Science Publishing Group SN - 2328-5591 UR - https://doi.org/10.11648/j.acis.s.2015030201.14 AB - Oral pathogenic gram-positive bacteria, Streptococcus pyogenes (Strept.pyogenes) are caused severe human diseases with complications, including rheumatic fever, sepsis, severe soft-tissue invasion, and toxic-shock-like syndrome (TSLS). Whereas, Streptococcus mutants(Strept. mutans),described a key causative agent of caries and infective endocarditis. Therefore, the aim of this study was to evaluate the inhibitory effect of Curcumin on Strept. mutans and Strept.pyogenes growth in comparison with the antibiotic Ciprofloxacin using well diffusion method. Minimum Inhibitory Concentration (MICs) showed that curcumin-mediated growth inhibition of Strept. mutans and, Strept. pyogenes. Results showed that curcumin significantly inhibitedthe activity of Strept. mutans and Strept. pyogenes growth with inhibition zones, 9.7mm and 10.2 mm, respectively while the inhibition zone of Ciprofloxacin 15.52mm to 13.4mm against Strept. mutans, Strept. pyogenes respectively.The antimicrobial activity of curcumin on Strept. mutans and Strept. pyogenes growth suggests that the curcumin may be useful for controlling dental biofilms, subsequently dental caries formation.This study provides significant insights into the therapeutic effect of curcumin against pathogenic gram positive bacteria, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of curcumin. VL - 3 IS - 2-1 ER -
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