Chronic Administration of <i>Bauhinia forficata</i> Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats

Henriette Gellert Moranza; Laerte Scanavaca-Júnior; Maria Isabel Mataqueiro; Antonio de Queiroz-Neto; Guilherme de Camargo Ferraz

doi:doi:10.11648/j.plant.s.2017050501.14

Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats

Henriette Gellert Moranza, Laerte Scanavaca-Júnior, Maria Isabel Mataqueiro, Antonio de Queiroz-Neto, Guilherme de Camargo Ferraz

Published in Plant (Volume 5, Issue 5-1)

Received: 30 January 2017 Accepted: 6 February 2017 Published: 6 March 2017

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

This study provides information about the effect of chronic ingestion of a decoction of Bauhinia forficata on the behavior of rats. The aim of this study was to investigate the exploratory activity, anxiety level, and blood glucose of healthy rats submitted to prolonged treatment with a decoction of B.forficata. Twenty male rats, aged two months and weighing approximately 145g were randomly distributed into two groups. The Bauhinia group freely ingested a decoction of B.forficata for 4 weeks, while the control group received water. Body weight, food and fluid intake, and glycemic index were quantified. The open field (OF) and elevated plus maze (EPM) tests were applied at the end of the experiment. Data were analyzed by Student’s t test for unpaired samples, with a significance level of P<0.05. The results of the EPM test were analyzed by the Wilcoxon Signed Rank Test and blood glucose by the Bonferroni test. There were no significant differences in body weight, food intake or glycemic index between the Bauhinia and control groups. Net liquid intake was higher in the Bauhinia group. EPM results did not differ between groups, but in the OF test, the frequencies of rearing and locomotion were lower and immobility time was increased for rats in the Bauhinia group. In conclusion, B.forficata reduced exploratory activity and did not alter blood glucose in healthy rats.

Published in	Plant (Volume 5, Issue 5-1) This article belongs to the Special Issue Phytotherapy
DOI	10.11648/j.plant.s.2017050501.14
Page(s)	27-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Behavior, Exploratory Activity, Ethnopharmacology

References

[1]	G. M. Costa-Silva, H. Silva, M. L. F. Cavalcanti, P. Martins, "Autecology of Bauhinia forficata L.: threatened species of extinction in the Caatinga ecosystem", Journal of Biology and Earth Sciences, vol.3, pp.1-15, 2003.
[2]	M. I. Silva, C. T. Melo, L. F. Vasconcelos, A. M. Carvalho, F. C. Sousa, "Bioactivity and potential therapeutic benefits of some medicinal plants from the Caatinga (semi-arid) vegetation of Northeast Brazil: a review of the literature", Braz Journal Pharmacognosy, vol. 22, pp. 193-207, Jan-Feb 2012.
[3]	G. T. Volpato, D. C. Damasceno, M. V. C. Rudge, C. R. Padovani, I. D. M. P. Calderon, "Effect of Bauhinia forficata aqueous extract on the maternal-fetal outcome and oxidative stress biomarkers of streptozotocin-induced diabetic rats", J Ethnopharmacol, vol.116, pp.131-37, Feb 2008.
[4]	I. S. Lopes, J. E. R. Silva, I. A. Machado, C. E. M. R. Silva, M. G. Marinho, J. A. F. Rangel, "Lifting of medicinal plants used in the city of Itapetim, Pernambuco, Brazil", Journal of Biology and Drugstore, vol. 7, pp. 115-21, 2012.
[5]	N. Jatav, A. Ganeshpurkar, N. Gupta, C. Ayachi, R. Ramhariya, D. Bansal, N. Dubey, "Nootropic potential of Bauhinia variegata: A systematic study on murine model", Archives of Medicine and Health Sciences, vol. 2, pp. 29-35, July-Dec 2014.
[6]	F. J. B. D. Santos, S. G. D. Lima, G. S. Cerqueira, A. M. D. G. L. Citó, A. A. D. C. Cavalcante, T. H. C. Marques, R. M. D. Freitas, "Chemical composition and anxiolytic-like effects of the Bauhinia platypetala" ,Braz Journal of Pharmacognosy, vol. 22, pp. 507-16, May-June 2012.
[7]	E. M. Cavalcanti, C. Bonafé, M. G. Silva, M. Gerenutti, "Properties of Bauhinia forficata Link in rats: behavioral evaluations", Pharmacologyonline, vol.2, pp.205-11, Agust 2011.
[8]	N. M. Khalil, M. T. Pepato, I. L. Brunetti, "Free radicals cavenging profile and myeloperoxidase in hibition of extracts from antidiabetic plants: Bauhinia forficata and Cissus sicyoides", Biological research, vol. 41, pp. 165-71, 2008.
[9]	S. M. Vasconcelos, D. S. Macedo, C. T. V Melo, A. P. Monteiro, G. Cunha, F. C. F. Sousa, E. R. Silveira, "Central activity of hydroalcoholic extracts from Erythrina velutina and Erythrina mulungu in mice", J Pharm Pharmacol, vol.56, pp. 389-93, March 2004.
[10]	V. G. Mota, F. L. Carvalho, L. C. S. L. Morais, J. Bhattacharyya, R. N. Almeida, J. L. Alencar, "Antinociceptive activity of the chloroform fraction of Dioclea virgata (Rich.) Amshoff (Fabaceae) in mice", J Biomed Biotechnol, vol. 2011, pp. 1-10, 2011.
[11]	R. Estrada-Reyes, D. Ubaldo-Suárez, A. G. Araujo-Escalona, "Los flavonoides y el Sistema Nervioso Central", Salud mental, vol.35, pp.375-84, Sept-Oct 2012.
[12]	M. S. Davey, C. Atlee, S. R. S. Ashok Bharathi, M. Farook, "Antianxiety effect of methanolic extract of Bauhinia racemosa (lamk) stems bark in mice", IJPBS, vol.2, pp.217-24, April-June 2011.
[13]	M. T. Pepato, A. M. Baviera, R. C. Vendramini, I. L. Brunetti, "Evaluation of toxicity after one-months treatment with Bauhinia forficata decoction in streptozotocin-induced diabetic rats", BMC, vol.4, pp.1, June 2004.
[14]	M. T. Pepato, E. H. Keller, A. M. Baviera , I. C. Kettelhut, R. C. Vendramini, I. L. Brunetti, "Anti-diabetic activity of Bauhinia forficata decoction in streptozotocin-diabetic rats", J Ethnopharmacol, vol. 81, pp.191-97, July 2002.

Cite This Article

Plain Text BibTeX RIS

APA Style

Henriette Gellert Moranza, Laerte Scanavaca-Júnior, Maria Isabel Mataqueiro, Antonio de Queiroz-Neto, Guilherme de Camargo Ferraz. (2017). Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant, 5(5-1), 27-32. https://doi.org/10.11648/j.plant.s.2017050501.14

Copy | Download

ACS Style

Henriette Gellert Moranza; Laerte Scanavaca-Júnior; Maria Isabel Mataqueiro; Antonio de Queiroz-Neto; Guilherme de Camargo Ferraz. Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant. 2017, 5(5-1), 27-32. doi: 10.11648/j.plant.s.2017050501.14

Copy | Download

AMA Style

Henriette Gellert Moranza, Laerte Scanavaca-Júnior, Maria Isabel Mataqueiro, Antonio de Queiroz-Neto, Guilherme de Camargo Ferraz. Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant. 2017;5(5-1):27-32. doi: 10.11648/j.plant.s.2017050501.14

Copy | Download

@article{10.11648/j.plant.s.2017050501.14,
  author = {Henriette Gellert Moranza and Laerte Scanavaca-Júnior and Maria Isabel Mataqueiro and Antonio de Queiroz-Neto and Guilherme de Camargo Ferraz},
  title = {Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats},
  journal = {Plant},
  volume = {5},
  number = {5-1},
  pages = {27-32},
  doi = {10.11648/j.plant.s.2017050501.14},
  url = {https://doi.org/10.11648/j.plant.s.2017050501.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.s.2017050501.14},
  abstract = {This study provides information about the effect of chronic ingestion of a decoction of Bauhinia forficata on the behavior of rats. The aim of this study was to investigate the exploratory activity, anxiety level, and blood glucose of healthy rats submitted to prolonged treatment with a decoction of B.forficata. Twenty male rats, aged two months and weighing approximately 145g were randomly distributed into two groups. The Bauhinia group freely ingested a decoction of B.forficata for 4 weeks, while the control group received water. Body weight, food and fluid intake, and glycemic index were quantified. The open field (OF) and elevated plus maze (EPM) tests were applied at the end of the experiment. Data were analyzed by Student’s t test for unpaired samples, with a significance level of PB.forficata reduced exploratory activity and did not alter blood glucose in healthy rats.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats
AU  - Henriette Gellert Moranza
AU  - Laerte Scanavaca-Júnior
AU  - Maria Isabel Mataqueiro
AU  - Antonio de Queiroz-Neto
AU  - Guilherme de Camargo Ferraz
Y1  - 2017/03/06
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.s.2017050501.14
DO  - 10.11648/j.plant.s.2017050501.14
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 27
EP  - 32
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.s.2017050501.14
AB  - This study provides information about the effect of chronic ingestion of a decoction of Bauhinia forficata on the behavior of rats. The aim of this study was to investigate the exploratory activity, anxiety level, and blood glucose of healthy rats submitted to prolonged treatment with a decoction of B.forficata. Twenty male rats, aged two months and weighing approximately 145g were randomly distributed into two groups. The Bauhinia group freely ingested a decoction of B.forficata for 4 weeks, while the control group received water. Body weight, food and fluid intake, and glycemic index were quantified. The open field (OF) and elevated plus maze (EPM) tests were applied at the end of the experiment. Data were analyzed by Student’s t test for unpaired samples, with a significance level of PB.forficata reduced exploratory activity and did not alter blood glucose in healthy rats.
VL  - 5
IS  - 5-1
ER  -

Copy | Download

Author Information

Henriette Gellert Moranza

Department of Animal Morphology and Physiology, Faculty of Agrarian and Veterinary Sciences, S?o Paulo State University, Jaboticabal, SP, Brazil
Laerte Scanavaca-Júnior

Brazilian Agricultural Research Corporation - EMBRAPA Environment, Jaguariúna, SP, Brazil
Maria Isabel Mataqueiro

Department of Animal Morphology and Physiology, Faculty of Agrarian and Veterinary Sciences, S?o Paulo State University, Jaboticabal, SP, Brazil
Antonio de Queiroz-Neto

Department of Animal Morphology and Physiology, Faculty of Agrarian and Veterinary Sciences, S?o Paulo State University, Jaboticabal, SP, Brazil
Guilherme de Camargo Ferraz

Department of Animal Morphology and Physiology, Faculty of Agrarian and Veterinary Sciences, S?o Paulo State University, Jaboticabal, SP, Brazil

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Henriette Gellert Moranza, Laerte Scanavaca-Júnior, Maria Isabel Mataqueiro, Antonio de Queiroz-Neto, Guilherme de Camargo Ferraz. (2017). Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant, 5(5-1), 27-32. https://doi.org/10.11648/j.plant.s.2017050501.14

Copy | Download

ACS Style

Henriette Gellert Moranza; Laerte Scanavaca-Júnior; Maria Isabel Mataqueiro; Antonio de Queiroz-Neto; Guilherme de Camargo Ferraz. Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant. 2017, 5(5-1), 27-32. doi: 10.11648/j.plant.s.2017050501.14

Copy | Download

AMA Style

Henriette Gellert Moranza, Laerte Scanavaca-Júnior, Maria Isabel Mataqueiro, Antonio de Queiroz-Neto, Guilherme de Camargo Ferraz. Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats. Plant. 2017;5(5-1):27-32. doi: 10.11648/j.plant.s.2017050501.14

Copy | Download

@article{10.11648/j.plant.s.2017050501.14,
  author = {Henriette Gellert Moranza and Laerte Scanavaca-Júnior and Maria Isabel Mataqueiro and Antonio de Queiroz-Neto and Guilherme de Camargo Ferraz},
  title = {Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats},
  journal = {Plant},
  volume = {5},
  number = {5-1},
  pages = {27-32},
  doi = {10.11648/j.plant.s.2017050501.14},
  url = {https://doi.org/10.11648/j.plant.s.2017050501.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plant.s.2017050501.14},
  abstract = {This study provides information about the effect of chronic ingestion of a decoction of Bauhinia forficata on the behavior of rats. The aim of this study was to investigate the exploratory activity, anxiety level, and blood glucose of healthy rats submitted to prolonged treatment with a decoction of B.forficata. Twenty male rats, aged two months and weighing approximately 145g were randomly distributed into two groups. The Bauhinia group freely ingested a decoction of B.forficata for 4 weeks, while the control group received water. Body weight, food and fluid intake, and glycemic index were quantified. The open field (OF) and elevated plus maze (EPM) tests were applied at the end of the experiment. Data were analyzed by Student’s t test for unpaired samples, with a significance level of PB.forficata reduced exploratory activity and did not alter blood glucose in healthy rats.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Chronic Administration of Bauhinia forficata Link Reduced Exploratory Activity Without Affecting Blood Glucose in Healthy Rats
AU  - Henriette Gellert Moranza
AU  - Laerte Scanavaca-Júnior
AU  - Maria Isabel Mataqueiro
AU  - Antonio de Queiroz-Neto
AU  - Guilherme de Camargo Ferraz
Y1  - 2017/03/06
PY  - 2017
N1  - https://doi.org/10.11648/j.plant.s.2017050501.14
DO  - 10.11648/j.plant.s.2017050501.14
T2  - Plant
JF  - Plant
JO  - Plant
SP  - 27
EP  - 32
PB  - Science Publishing Group
SN  - 2331-0677
UR  - https://doi.org/10.11648/j.plant.s.2017050501.14
AB  - This study provides information about the effect of chronic ingestion of a decoction of Bauhinia forficata on the behavior of rats. The aim of this study was to investigate the exploratory activity, anxiety level, and blood glucose of healthy rats submitted to prolonged treatment with a decoction of B.forficata. Twenty male rats, aged two months and weighing approximately 145g were randomly distributed into two groups. The Bauhinia group freely ingested a decoction of B.forficata for 4 weeks, while the control group received water. Body weight, food and fluid intake, and glycemic index were quantified. The open field (OF) and elevated plus maze (EPM) tests were applied at the end of the experiment. Data were analyzed by Student’s t test for unpaired samples, with a significance level of PB.forficata reduced exploratory activity and did not alter blood glucose in healthy rats.
VL  - 5
IS  - 5-1
ER  -

Copy | Download