This project report describes the biological activity of the dried leaves of Mangifera indica belonging to the family Anacardiaceae and the dried fruits of Areca catechu belonging to the family Arecaceae. The dried powders of leaves and fruits were extracted with organic solvents –Carbon tetrachloride, Methanol & Pet ether sequentially by maceration process. After this, The crude extracts of Carbon tetrachloride, Methanol & Pet ether were investigated for analgesic and antimicrobial property. For Mangifera indica, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were studied for analgesic property at an oral dose of 200 mg /kg of body weight using acetic acid induced writhing effect method. The result showed that the Methanol and Pet ether extracts had mild analgesic property (having a writhing inhibition of 51.7% and 50% respectively), while carbon tetrachloride extract did not show significant analgesic property (having a writhing inhibition of 30 %). For Areca catechu, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were screened for antimicrobial activity against gram positive and gram negative bacteria and fungi using disk diffusion method. The results obtained were compared with that of standard drug kanamycin. The Carbon tetrachloride extract showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 9-10 mm). The Methanol extract also showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 7-10 mm).and slightly to highly sensitive to fungi (zone of inhibition 8-40 mm). The pet ether extract Crystal (Found after adding Carbon tetrachloride) showed mild sensitivity to only a gram negative bacteria (Shigella boydii) having zone of inhibition 7 mm.
| Published in |
American Journal of BioScience (Volume 3, Issue 2-1)
This article belongs to the Special Issue Pharmacological and Phytochemicals Investigation |
| DOI | 10.11648/j.ajbio.s.2015030201.14 |
| Page(s) | 19-22 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2015. Published by Science Publishing Group |
Mangifera indica, Anacardiaceae, Areca catechu Arecaceae, Antimicrobial Activity, Disc Diffusion Method, Analgesic Activity, Writhing Effect
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| [7] | Reyad-ul-Ferdous M, Alam TT, Islam MA, Khan MZI, Tasnim F, et al (2014) Ex-Vivo Cardioprotective and Cytotoxic Screening of Fruits of Parmentiera ereifera Seem. Biol Med 6: 219. doi: 10.4172/0974-8369.1000219. |
| [8] | Md. Reyad-Ul-Ferdous, Sayma Akhter, Md. Zahirul Islam Khan, Md. Eshak Khan, Md. Atiqul Islam, Md. Sharif Ullah. Ex-Vivo Anti-Inflammatory and Antimicrobial Activities of the Leaves of Bauhinia acuminata. American Journal of Life Sciences. Vol. 2, No. 5, 2014, pp. 267-270. doi: 10.11648/j.ajls.20140205.13. |
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APA Style
Mst. Marium Begum, Taslima Begum, Mohammad Ashikur Rahman, Tahmina Haque, Md. Abir Khan, et al. (2015). Potential In-Vivo Evaluation of Analgesic Investigation of Mangifera indica and Antimicrobial Activity of Areca catechu. American Journal of BioScience, 3(2-1), 19-22. https://doi.org/10.11648/j.ajbio.s.2015030201.14
ACS Style
Mst. Marium Begum; Taslima Begum; Mohammad Ashikur Rahman; Tahmina Haque; Md. Abir Khan, et al. Potential In-Vivo Evaluation of Analgesic Investigation of Mangifera indica and Antimicrobial Activity of Areca catechu. Am. J. BioScience 2015, 3(2-1), 19-22. doi: 10.11648/j.ajbio.s.2015030201.14
AMA Style
Mst. Marium Begum, Taslima Begum, Mohammad Ashikur Rahman, Tahmina Haque, Md. Abir Khan, et al. Potential In-Vivo Evaluation of Analgesic Investigation of Mangifera indica and Antimicrobial Activity of Areca catechu. Am J BioScience. 2015;3(2-1):19-22. doi: 10.11648/j.ajbio.s.2015030201.14
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Download@article{10.11648/j.ajbio.s.2015030201.14,
author = {Mst. Marium Begum and Taslima Begum and Mohammad Ashikur Rahman and Tahmina Haque and Md. Abir Khan and Md. Belal Hossain and Hasan Tarek and Md. Noor-A-Alam and Md. Reyad-ul- Ferdous and Md. Safkath Ibne Jami},
title = {Potential In-Vivo Evaluation of Analgesic Investigation of Mangifera indica and Antimicrobial Activity of Areca catechu},
journal = {American Journal of BioScience},
volume = {3},
number = {2-1},
pages = {19-22},
doi = {10.11648/j.ajbio.s.2015030201.14},
url = {https://doi.org/10.11648/j.ajbio.s.2015030201.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.s.2015030201.14},
abstract = {This project report describes the biological activity of the dried leaves of Mangifera indica belonging to the family Anacardiaceae and the dried fruits of Areca catechu belonging to the family Arecaceae. The dried powders of leaves and fruits were extracted with organic solvents –Carbon tetrachloride, Methanol & Pet ether sequentially by maceration process. After this, The crude extracts of Carbon tetrachloride, Methanol & Pet ether were investigated for analgesic and antimicrobial property. For Mangifera indica, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were studied for analgesic property at an oral dose of 200 mg /kg of body weight using acetic acid induced writhing effect method. The result showed that the Methanol and Pet ether extracts had mild analgesic property (having a writhing inhibition of 51.7% and 50% respectively), while carbon tetrachloride extract did not show significant analgesic property (having a writhing inhibition of 30 %). For Areca catechu, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were screened for antimicrobial activity against gram positive and gram negative bacteria and fungi using disk diffusion method. The results obtained were compared with that of standard drug kanamycin. The Carbon tetrachloride extract showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 9-10 mm). The Methanol extract also showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 7-10 mm).and slightly to highly sensitive to fungi (zone of inhibition 8-40 mm). The pet ether extract Crystal (Found after adding Carbon tetrachloride) showed mild sensitivity to only a gram negative bacteria (Shigella boydii) having zone of inhibition 7 mm.},
year = {2015}
}
TY - JOUR T1 - Potential In-Vivo Evaluation of Analgesic Investigation of Mangifera indica and Antimicrobial Activity of Areca catechu AU - Mst. Marium Begum AU - Taslima Begum AU - Mohammad Ashikur Rahman AU - Tahmina Haque AU - Md. Abir Khan AU - Md. Belal Hossain AU - Hasan Tarek AU - Md. Noor-A-Alam AU - Md. Reyad-ul- Ferdous AU - Md. Safkath Ibne Jami Y1 - 2015/02/27 PY - 2015 N1 - https://doi.org/10.11648/j.ajbio.s.2015030201.14 DO - 10.11648/j.ajbio.s.2015030201.14 T2 - American Journal of BioScience JF - American Journal of BioScience JO - American Journal of BioScience SP - 19 EP - 22 PB - Science Publishing Group SN - 2330-0167 UR - https://doi.org/10.11648/j.ajbio.s.2015030201.14 AB - This project report describes the biological activity of the dried leaves of Mangifera indica belonging to the family Anacardiaceae and the dried fruits of Areca catechu belonging to the family Arecaceae. The dried powders of leaves and fruits were extracted with organic solvents –Carbon tetrachloride, Methanol & Pet ether sequentially by maceration process. After this, The crude extracts of Carbon tetrachloride, Methanol & Pet ether were investigated for analgesic and antimicrobial property. For Mangifera indica, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were studied for analgesic property at an oral dose of 200 mg /kg of body weight using acetic acid induced writhing effect method. The result showed that the Methanol and Pet ether extracts had mild analgesic property (having a writhing inhibition of 51.7% and 50% respectively), while carbon tetrachloride extract did not show significant analgesic property (having a writhing inhibition of 30 %). For Areca catechu, the crude extracts of Carbon tetrachloride, Methanol & Pet ether were screened for antimicrobial activity against gram positive and gram negative bacteria and fungi using disk diffusion method. The results obtained were compared with that of standard drug kanamycin. The Carbon tetrachloride extract showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 9-10 mm). The Methanol extract also showed mild sensitivity to several gram positive, gram negative bacteria & Fungi (zone of inhibition 7-10 mm).and slightly to highly sensitive to fungi (zone of inhibition 8-40 mm). The pet ether extract Crystal (Found after adding Carbon tetrachloride) showed mild sensitivity to only a gram negative bacteria (Shigella boydii) having zone of inhibition 7 mm. VL - 3 IS - 2-1 ER -
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